Product Overview

• Active Ingredient: Linezolid
• Dosage Form: Film-coated tablets
• Strength: 600 mg
• Drug Class: Oxazolidinone antibiotics
• Approval Date: 2000

Indications

Linezolid is indicated for treating the following infections in adults and pediatric patients:

• Nosocomial Pneumonia
• Community-Acquired Pneumonia
• Complicated Skin and Skin Structure Infections (including diabetic foot infections without osteomyelitis)
• Uncomplicated Skin and Skin Structure Infections
• Vancomycin-Resistant Enterococcus faecium Infections

Note: Not effective against Gram-negative infections.

Dosage and Administration

Adults:

• 600 mg every 12 hours (oral/IV)

Pediatric:

• 10 mg/kg every 8 hours (oral/IV)
• Duration varies by condition (10 to 28 days)

Renal Impairment: Dose adjustments may be required.

Contraindications

• Hypersensitivity to Linezolid
• Concurrent use with MAO inhibitors

Warnings and Precautions

• Myelosuppression: Regular blood count monitoring
• Peripheral and Optic Neuropathy: Monitor visual function
• Serotonin Syndrome: Caution with serotonergic agents
• Clostridioides difficile-Associated Diarrhea (CDAD): Monitor for symptoms
• Blood Pressure Monitoring: Necessary in hypertensive patients
• Hypoglycemia: Caution in diabetic patients

Common Side Effects

• Diarrhea
• Nausea
• Headache
• Vomiting
• Anemia

Drug Interactions

• MAO Inhibitors: Avoid concomitant use
• Serotonergic Agents: Increased risk of serotonin syndrome

Storage

• Store at 20°C to 25°C (68°F to 77°F).
• Protect from light and moisture.

Patient Counseling

• Inform your healthcare provider of any history of high blood pressure, diabetes, or use of MAO inhibitors.
• Report any signs of visual impairment, prolonged diarrhea, or unusual bruising/bleeding.

Note: 

The brand name displayed above is specific to this product. Brand names can vary depending on the manufacturer.